GOING ABOVE AND BEYOND

RESEARCH SERVICES
In Vitro ADME/Tox

  • Compound Purity, Solubility, Dissolution and Chemical Stability

  • Caco-2 Permeability
  • Metabolic Stability
  • CYP450 Inhibition
  • CYP450 Induction
  • CYP450 Phenotyping
  • UGT Inhibition
  • UGT Phenotyping
  • Uptake Transporter Inhibition
  • Uptake Transporter Phenotyping
  • Efflux Transporter Inhibition
  • Efflux Transporter Phenotyping
  • Additional Drug-Metabolizing Enzyme Phenotyping (FMOs, MAOs, AOs, ALDH, ADH)
  • Plasma or Whole Blood Stability
  • Blood-to-Plasma Partitioning
  • Plasma Protein Binding
  • Tissue Binding
  • Drug Metabolite Profiling and Structural Identification
  • GSH Trapping for Reactive Metabolites Formation
  • Cytotoxicity
  • Hemolysis‚Äč